Evaluation and Management
 99217       Observation care discharge day management (This code is to be utilized to report all services provided to a patient on discharge from outpatient hospital “observation status” if the discharge is on other than the initial date of “observation status.” To report services to a patient designated as “observation status” or “inpatient status” and discharged on the same date, use the codes for Observation or Inpatient Care Services [including Admission and Discharge Services, 99234-99236 as appropriate.])
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 99218      Initial observation care, per day, for the evaluation and management of a patient which requires these 3 key components:
A detailed or comprehensive history;
A detailed or comprehensive examination; and
Medical decision making that is straightforward or of low complexity.
Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient’s and/or family’s needs.
Usually, the problem(s) requiring admission to outpatient hospital “observation status” are of low severity. Typically, 30 minutes are spent at the bedside and on the patient’s hospital floor or unit.
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 99219     Initial observation care, per day, for the evaluation and management of a patient, which requires these 3 key components:
A comprehensive history;
A comprehensive examination; and
Medical decision making of moderate complexity.
Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient’s and/or family’s needs.
Usually, the problem(s) requiring admission to outpatient hospital “observation status” are of moderate severity. Typically, 50 minutes are spent at the bedside and on the patient’s hospital floor or unit.
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99220Â Â Â Â Â Â Initial observation care, per day, for the evaluation and management of a patient, which requires these 3 key components:
A comprehensive history;
A comprehensive examination; and
Medical decision making of high complexity.
Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient’s and/or family’s needs.
Usually, the problem(s) requiring admission to outpatient hospital “observation status” are of high severity. Typically, 70 minutes are spent at the bedside and on the patient’s hospital floor or unit.
17250Â Â Â Â Chemical cauterization of granulation tissue (ie, proud flesh) sinus or fistula)
 31254    Nasal/sinus endoscopy, surgical; with ethmoidectomy, with ethmoidectomy;partial (anterior)
31255Â Â Â Â Â Â Â Â Â Â with ethmoidectomy;total (anterior and posterior)
 31276      Nasal/sinus endoscopy, surgical with frontal sinus exploration, with or without including removal of tissue from frontal sinus,when performed
31645Â Â Â Â Â Â with therapeutic aspiration of tracheobronchial tree, initial (eg, drainage of lung abscess)
31646Â Â Â Â Â with therapeutic aspiration of tracheobronchial tree, subsequent, same hospital stay
32998Â Â Â Â Â Ablation therapy for reduction or eradication of 1 or more pulmonary tumor(s) including pleura or chest wall when involved by tumor extension, percutaneous, radiofrequency including imaging guidance when performed, unilateral; radiofrequency
34812Â Â Â Â Â Open femoral artery exposure for delivery of endovascular prosthesis, by groin incision, unilateral (List separately in addition to code for primary procedure)
34820Â Â Â Â Â Open iliac artery exposure for delivery of endovascular prosthesis or iliac occlusion during endovascular therapy, by abdominal or retroperitoneal incision, unilateral (List separately in addition to code for primary procedure)
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 34833    Open iliac artery exposure with creation of conduit for delivery of aortic or iliac endovascular prosthesis or for establishment of cardiopulmonary bypass, by abdominal or retroperitoneal incision, unilateral (List separately in addition to code for primary procedure)
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 34834    Open brachial artery exposure to assist in the deployment of aortic or iliac endovascular prosthesis by arm incision, unilateraly for delivery of endovascular prosthesis, unilateral (List separately in addition to code for primary procedure)
36140Â Â Â Â Â Introduction of needle or intracatheter, upper or lower extremity artery extremity artery
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36468Â Â Â Â Â Â Â Â Single or multiple injections Injection(s) of sclerosing solutions;sclerosant for spider veins (telangiectasia), limb or trunk
36470Â Â Â Â Â Injection of sclerosin solution sclerosant; single incompetent vein (other than telangiectasia)
 36471     multiple incompetent veins (other than telangiectasia), same leg
36516Â Â Â Â Â with extracorporeal immunoadsorption, selective adsorption or selective filtration and plasma reinfusion
36908Â Â Â Â Transcatheter placement of intravascular stent(s), central dialysis segment, performed through dialysis circuit, including all imaging and radiological supervision and interpretation required to perform the stenting, and all angioplasty in the central dialysis segment (List separately in addition to code for primary procedure)
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38220Â Â Â Â Â Â Â Bone Diagnostic bone marrow; aspiration only(s)
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38221Â Â Â Â Â biopsy; needle or tracar(ies)
43112Â Â Â Â Â Total or near total esophagectomy, with thoracotomy; with pharyngogastrostomy or cervical esophagogastrostomy, with or without pyloroplasty (ie, McKeown esophagectomy or tri-incisional esophagectomy)
57240Â Â Â Â Â Anterior colporrhaphy, repair of cystocele with or without repair of urethrocele, including cystourethroscopy, when performed
57260Â Â Â Â Â Â Combined anteroposterior colporrhaphy, including cystourethroscopy, when performed;
57265Â Â Â Â Â Â with enterocele repair
64550Â Â Â Â Â Application of surface (transcutaneous) neurostimulator (eg, TENS unit)
76000Â Â Â Â Â Fluoroscopy (separate procedure), up to 1 hour physician or other qualified health care professional time other than 71023 or 71034 (eg, cardiac fluoroscopy)
76881Â Â Â Â Â Ultrasound, extremity, nonvascular; complete joint (ie, joint space and peri-articular soft tissue structures) real-time with image documentation: complete
76882Â Â Â Â Â Ultrasound, limited, anatomic specific joint or other nonvascular extremity structure(s) (eg, joint space, peri-articular tendon[s], muscle[s], nerve[s], other soft tissue structure[s], or soft tissue mass[es]), real-time with image documentation
 80305    Drug test(s), presumptive, any number of drug classes, any number of devices or procedures; (eg, immunoassay); capable of being read by direct optical observation only (eg, dipsticks utilizing immunoassay [eg, dipsticks, cups, cards, or cartridges]), includes sample validation when performed, per date of service
80306Â Â Â Â Â read by instrument assisted direct optical observation (eg, dipsticks utilizing immunoassay [eg, dipsticks, cups, cards, or cartridges]), includes sample validation when performed, per date of service
80307Â Â Â Â Â by instrument chemistry analyzers (eg, utilizing immunoassay [eg, EIA, ELISA, EMIT, FPIA, IA, KIMS, RIA]), chromatography (eg, GC, HPLC), and mass spectrometry either with or without chromatography, (eg, DART, DESI, GC-MS, GC-MS/MS, LC-MS, LC-MS/MS, LDTD, MALDI, TOF) includes sample validation when performed, per date of service
81257Â Â Â Â Â HBA1/HBA2 (alpha globin 1 and alpha globin 2) (eg, alpha thalassemia, Hb Bart hydrops fetalis syndrome, HbH disease), gene analysis;, for common deletions or variant (eg, Southeast Asian, Thai, Filipino, Mediterranean, alpha3.7, alpha4.2, alpha20.5, Constant Spring)
81400Â Â Â Â Â Molecular pathology procedure, Level 1 (eg, identification of single germline variant [eg, SNP] by techniques such as restriction enzyme digestion or melt curve analysis)
DPYD (dihydropyrimidine dehydrogenase) (eg, 5-fluorouracil/5-FU and capecitabine drug metabolism), IVS14+1GA variant
Human Platelet Antigen 1 genotyping (HPA-1), ITGB3 (integrin, beta 3 [platelet glycoprotein IIIa], antigen CD61 [GPIIIa]) (eg, neonatal alloimmune thrombocytopenia [NAIT], post-transfusion purpura), HPA-1a/b (L33P)
Human Platelet Antigen 2 genotyping (HPA-2), GP1BA (glycoprotein Ib [platelet], alpha polypeptide [GPIba]) (eg, neonatal alloimmune thrombocytopenia [NAIT], post-transfusion purpura), HPA-2a/b (T145M)
Human Platelet Antigen 3 genotyping (HPA-3), ITGA2B (integrin, alpha 2b [platelet glycoprotein IIb of IIb/IIIa complex], antigen CD41 [GPIIb]) (eg, neonatal alloimmune thrombocytopenia [NAIT], post-transfusion purpura), HPA-3a/b (I843S)
Human Platelet Antigen 4 genotyping (HPA-4), ITGB3 (integrin, beta 3 [platelet glycoprotein IIIa], antigen CD61 [GPIIIa]) (eg, neonatal alloimmune thrombocytopenia [NAIT], post-transfusion purpura), HPA-4a/b (R143Q)
Human Platelet Antigen 5 genotyping (HPA-5), ITGA2 (integrin, alpha 2 [CD49B, alpha 2 subunit of VLA-2 receptor] [GPIa]) (eg, neonatal alloimmune thrombocytopenia [NAIT], post-transfusion purpura), HPA-5a/b (K505E)
Human Platelet Antigen 6 genotyping (HPA-6w), ITGB3 (integrin, beta 3 [platelet glycoprotein IIIa, antigen CD61] [GPIIIa]) (eg, neonatal alloimmune thrombocytopenia [NAIT], post-transfusion purpura), HPA-6a/b (R489Q)
Human Platelet Antigen 9 genotyping (HPA-9w), ITGA2B (integrin, alpha 2b [platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41] [GPIIb]) (eg, neonatal alloimmune thrombocytopenia [NAIT], post-transfusion purpura), HPA-9a/b (V837M)
Human Platelet Antigen 15 genotyping (HPA-15), CD109 (CD109 molecule) (eg, neonatal alloimmune thrombocytopenia [NAIT], post-transfusion purpura), HPA-15a/b (S682Y)
IL28B (interleukin 28B [interferon, lambda 3]) (eg, drug response), rs12979860 variant
SLCO1B1 (solute carrier organic anion transporter family, member 1B1) (eg, adverse drug reaction), V174A variant
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81401Â Â Â Â Molecular pathology procedure, Level 2 (eg, 2-10 SNPs, 1 methylated variant, or 1 somatic variant [typically using nonsequencing target variant analysis], or detection of a dynamic mutation disorder/triplet repeat)
CYP3A4 (cytochrome P450, family 3, subfamily A, polypeptide 4) (eg, drug metabolism), common variants (eg, *2, *3, *4, *5, *6)
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CYP3A5 (cytochrome P450, family 3, subfamily A, polypeptide 5) (eg, drug metabolism), common variants (eg, *2, *3, *4, *5, *6)
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HBB (hemoglobin, beta) (eg, sickle cell anemia, hemoglobin C, hemoglobin E), common variants (eg, HbS, HbC, HbE)
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LINC00518 (long intergenic non-protein coding RNA 518) (eg, melanoma), expression analysis
PRAME (preferentially expressed antigen in melanoma) (eg, melanoma), expression analysis
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TPMT (thiopurine S-methyltransferase) (eg, drug metabolism), common variants (eg, *2, *3)
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TYMS (thymidylate synthetase) (eg, 5-fluorouracil/5-FU drug metabolism), tandem repeat variant
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81403Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Molecular pathology procedure, Level 4 (eg, analysis of single exon by DNA sequence analysis, analysis of 10 amplicons using multiplex PCR in 2 or more independent reactions, mutation scanning or duplication/deletion variants of 2-5 exons)
HBB (hemoglobin, beta, beta-globin) (eg, beta thalassemia), duplication/deletion analysis
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IDH1 (isocitrate dehydrogenase 1 [NADP+], soluble) (eg, glioma), common exon 4 variants (eg, R132H, R132C)
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IDH2 (isocitrate dehydrogenase 2 [NADP+], mitochondrial) (eg, glioma), common exon 4 variants (eg, R140W, R172M)
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 81404      Molecular pathology procedure, Level 5 (eg, analysis of 2-5 exons by DNA sequence analysis, mutation scanning or duplication/deletion variants of 6-10 exons, or characterization of a dynamic mutation disorder/triplet repeat by Southern blot analysis)
HBA1/HBA2 (alpha globin 1 and alpha globin 2) (eg, alpha thalassemia), duplication/deletion analysis
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HBB (hemoglobin, beta, Beta-Globin) (eg, thalassemia), full gene sequence
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 81405       Molecular pathology procedure, Level 6 (eg, analysis of 6-10 exons by DNA sequence analysis, mutation scanning or duplication/deletion variants of 11-25 exons, regionally targeted cytogenomic array analysis)
CPOX (coproporphyrinogen oxidase) (eg, hereditary coproporphyria), full gene sequence
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CTRC (chymotrypsin C) (eg, hereditary pancreatitis), full gene sequence
F9 (coagulation factor IX) (eg, hemophilia B), full gene sequence
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HBA1/HBA2 (alpha globin 1 and alpha globin 2) (eg, thalassemia), full gene sequence
PKLR (pyruvate kinase, liver and RBC) (eg, pyruvate kinase deficiency), full gene sequence
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 81406      Molecular pathology procedure, Level 7 (eg, analysis of 11-25 exons by DNA sequence analysis, mutation scanning or duplication/deletion variants of 26-50 exons, cytogenomic array analysis for neoplasia)
ANOS1 (anosmin-1) (eg, Kallmann syndrome 1), full gene sequence
HMBS (hydroxymethylbilane synthase) (eg, acute intermittent porphyria), full gene sequence
KAL1 (Kallmann syndrome 1 sequence) (eg, Kallmann syndrome), full gene sequence
PPOX(protoporphyrinogen oxidase) (eg, variegate porphyria), full gene sequence
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