There is separate ICD 10 coding guideline for coding sepsis, severe sepsis and Septic shock. We have to code multiple or more than one ICD 10 code for coding sepsis. Many coders make lot of mistakes in coding Sepsis. Hence, it is very important to know about the ICD 10 codes for coding sepsis. So, I am going to share the list of ICD 10 codes for coding sepsis. Do remember to read the ICD 10 coding guideline first before coding sepsis codes.

Superb ICD 10 coding tips for Sepsis


ICD 10 coding list for Sepsis

A40 Streptococcal sepsis

Code first postprocedural streptococcal sepsis (T81.4-) streptococcal sepsis during labor (O75.3)

streptococcal sepsis following abortion or ectopic or molar pregnancy (O03-O07, O08.0) streptococcal sepsis following immunization (T88.0)

streptococcal sepsis following infusion, transfusion or therapeutic injection (T80.2-)

Excludes1: neonatal (P36.0-P36.1) puerperal sepsis (O85)

sepsis due to Streptococcus, group D (A41.81)

A40.0 Sepsis due to streptococcus, group A

A40.1 Sepsis due to streptococcus, group B

A40.3 Sepsis due to Streptococcus pneumoniae

Pneumococcal sepsis

A40.8 Other streptococcal sepsis

A40.9 Streptococcal sepsis, unspecified


A41 Other sepsis

Code first postprocedural sepsis (T81.4-) sepsis during labor (O75.3)

sepsis following abortion, ectopic or molar pregnancy (O03-O07, O08.0) sepsis following immunization (T88.0)

sepsis following infusion, transfusion or therapeutic injection (T80.2-)

Excludes1: bacteremia NOS (R78.81) neonatal (P36.-) puerperal sepsis (O85) streptococcal sepsis (A40.-)

Excludes2: sepsis (due to) (in) actinomycotic (A42.7) sepsis (due to) (in) anthrax (A22.7) sepsis (due to) (in) candidal (B37.7) sepsis (due to) (in) Erysipelothrix (A26.7)

sepsis (due to) (in) extraintestinal yersiniosis (A28.2) sepsis (due to) (in) gonococcal (A54.86)

sepsis (due to) (in) herpesviral (B00.7) sepsis (due to) (in) listerial (A32.7) sepsis (due to) (in) melioidosis (A24.1)

sepsis (due to) (in) meningococcal (A39.2-A39.4) sepsis (due to) (in) plague (A20.7)

sepsis (due to) (in) tularemia (A21.7) toxic shock syndrome (A48.3)

A41.0 Sepsis due to Staphylococcus aureus

A41.01 Sepsis due to Methicillin susceptible Staphylococcus aureus

MSSA sepsis

Staphylococcus aureus sepsis NOS

A41.02 Sepsis due to Methicillin resistant Staphylococcus aureus

A41.1 Sepsis due to other specified staphylococcus

Coagulase negative staphylococcus sepsis

A41.2 Sepsis due to unspecified staphylococcus

A41.3 Sepsis due to Hemophilus influenzae

A41.4 Sepsis due to anaerobes

Excludes1: gas gangrene (A48.0)

A41.5 Sepsis due to other Gram-negative organisms

A41.50 Gram-negative sepsis, unspecified

Gram-negative sepsis NOS

A41.51 Sepsis due to Escherichia coli [E. coli]

A41.52 Sepsis due to Pseudomonas

Pseudomonas aeroginosa

A41.53 Sepsis due to Serratia

A41.59 Other Gram-negative sepsis

A41.8 Other specified sepsis

A41.81 Sepsis due to Enterococcus

A41.89 Other specified sepsis

A41.9 Sepsis, unspecified organism

Septicemia NOS



A42 Actinomycosis

Excludes1: actinomycetoma (B47.1)

A42.0 Pulmonary actinomycosis

A42.1 Abdominal actinomycosis

A42.2 Cervicofacial actinomycosis

A42.7 Actinomycotic sepsis

A42.8 Other forms of actinomycosis

A42.81 Actinomycotic meningitis

A42.82 Actinomycotic encephalitis

A42.89 Other forms of actinomycosis

A42.9 Actinomycosis, unspecified

A43 Nocardiosis

A43.0 Pulmonary nocardiosis

A43.1 Cutaneous nocardiosis

A43.8 Other forms of nocardiosis

A43.9 Nocardiosis, unspecified


A44 Bartonellosis

A44.0 Systemic bartonellosis

Oroya fever

A44.1 Cutaneous and mucocutaneous bartonellosis

Verruga peruana

A44.8 Other forms of bartonellosis

A44.9 Bartonellosis, unspecified


A46 Erysipelas

Excludes1: postpartum or puerperal erysipelas (O86.89)

A48 Other bacterial diseases, not elsewhere classified

Excludes1: actinomycetoma (B47.1)


A48.0 Gas gangrene

Clostridial cellulitis

Clostridial myonecrosis

A48.1 Legionnaires’ disease

A48.2 Nonpneumonic Legionnaires’ disease [Pontiac fever]

A48.3 Toxic shock syndrome

Use additional code to identify the organism (B95, B96)

Excludes1: endotoxic shock NOS (R57.8) sepsis NOS (A41.9)

A48.4 Brazilian purpuric fever

Systemic Hemophilus aegyptius infection

A48.5 Other specified botulism

Non-foodborne intoxication due to toxins of Clostridium botulinum [C. botulinum]

Excludes1: food poisoning due to toxins of Clostridium botulinum (A05.1)

A48.51 Infant botulism

A48.52 Wound botulism

Non-foodborne botulism NOS

Use additional code for associated wound

A48.8 Other specified bacterial diseases


A49 Bacterial infection of unspecified site

Excludes1: bacterial agents as the cause of diseases classified elsewhere (B95-B96) chlamydial infection NOS (A74.9)

meningococcal infection NOS (A39.9) rickettsial infection NOS (A79.9) spirochetal infection NOS (A69.9)

A49.0 Staphylococcal infection, unspecified site

A49.01 Methicillin susceptible Staphylococcus aureus infection, unspecified site

Methicillin susceptible Staphylococcus aureus (MSSA) infection

Staphylococcus aureus infection NOS

A49.02 Methicillin resistant Staphylococcus aureus infection, unspecified site

Methicillin resistant Staphylococcus aureus (MRSA) infection

A49.1 Streptococcal infection, unspecified site

A49.2 Hemophilus influenzae infection, unspecified site

A49.3 Mycoplasma infection, unspecified site

A49.8 Other bacterial infections of unspecified site

A49.9 Bacterial infection, unspecified

Excludes1: bacteremia NOS (R78.81)